Center for Infectious Disease and Vector Research

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IIGB Seminar Speaker - Dr. E. Terry Papoutsakis

Friday, October 13, 2017
12:101 p.m.


Genomics Building
Parking Information


Dear Faculty, Postdocs, Students, and Friends:

You are cordially invited to attend a special seminar presented by the Institute for Integrative Genome Biology


Dr. E. Terry Papoutsakis

Chemical & Biomolecular Engineering

University of Delaware



“101 Years of Clostridial Biotechnologies”

DATE: Friday, October, 13 2017

 LOCATION: Genomics Auditorium, RM 1102A

Time: 12:10 Pm


Host: Dr. Ian Wheeldon


2016 marked the 100th anniversary of the first industrial operation of the Acetone-Butanol-Ethanol (ABE) fermentation, based on the Weizmann Clostridium acetobutylicum strain. The ABE fermentation is widely celebrated and studied for its impact on industrial biotechnology, war, and patent policies.  It was originally used to produce acetone for the manufacturing of explosives, but after World-War I, the focus turned to butanol to manufacture lacquers for the car industry. C. acetobutylicum has been established not only as a model organism for the ABE fermentation but also for clostridial genetics and physiology. The last 15-20 years have seen great progress in understanding the genetic and physiology but also the engineering of this and many other clostridia, an ever-expanding list of them in fact. Organisms of importance to production of chemicals and fuels, cellulose and hemicellulose degradation, CO2 fixation (the “acetogens” among clostridia), but also those of importance to human health, notably those of importance to human microbiome, and the human pathogens. My goal is to provide a brief historical perspective of the field, and then emphasize recent advances and future needs to advance clostridial biotechnologies, which have come a long way from obscurity to prominence.

Additional Information:

Open to:

General Public




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